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Title:

Combined assessment of DYRK1A, BDNF and homocysteine levels as diagnostic marker for Alzheimer's disease.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Janel, N; Alexopoulos, P; Badel, A; Lamari, F; Camproux, A C; Lagarde, J; Simon, S; Feraudet-Tarisse, C; Lamourette, P; Arbones, M; Paul, J L; Dubois, B; Potier, M C; Sarazin, M; Delabar, J M
Abstract:
Early identification of Alzheimer's disease (AD) risk factors would aid development of interventions to delay the onset of dementia, but current biomarkers are invasive and/or costly to assess. Validated plasma biomarkers would circumvent these challenges. We previously identified the kinase DYRK1A in plasma. To validate DYRK1A as a biomarker for AD diagnosis, we assessed the levels of DYRK1A and the related markers brain-derived neurotrophic factor (BDNF) and homocysteine in two unrelated AD pa...     »
Journal title abbreviation:
Transl Psychiatry
Year:
2017
Journal volume:
7
Journal issue:
6
Pages contribution:
e1154
Language:
eng
Fulltext / DOI:
doi:10.1038/tp.2017.123
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28632203
Print-ISSN:
2158-3188
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie
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