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Titel:

A cerebrospinal fluid microRNA signature as biomarker for glioblastoma.

Dokumenttyp:
Journal Article
Autor(en):
Akers, Johnny C; Hua, Wei; Li, Hongying; Ramakrishnan, Valya; Yang, Zixiao; Quan, Kai; Zhu, Wei; Li, Jie; Figueroa, Javier; Hirshman, Brian R; Miller, Brittney; Piccioni, David; Ringel, Florian; Komotar, Ricardo; Messer, Karen; Galasko, Douglas R; Hochberg, Fred; Mao, Ying; Carter, Bob S; Chen, Clark C
Abstract:
To develop a cerebrospinal fluid (CSF) miRNA diagnostic biomarker for glioblastoma.Glioblastoma tissue and matched CSF from the same patient (obtained prior to tumor manipulation) were profiled by TaqMan OpenArray Human MicroRNA Panel. CSF miRNA profiles from glioblastoma patients and controls were created from three discovery cohorts and confirmed in two validation cohorts.miRNA profiles from clinical CSF correlated with those found in glioblastoma tissues. Comparison of CSF miRNA profiles betw...     »
Zeitschriftentitel:
Oncotarget
Jahr:
2017
Band / Volume:
8
Heft / Issue:
40
Seitenangaben Beitrag:
68769-68779
Sprache:
eng
Volltext / DOI:
doi:10.18632/oncotarget.18332
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28978155
TUM Einrichtung:
Neurochirurgische Klinik und Poliklinik
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