Health-related quality of life in children and adolescents: Current normative data, determinants and reliability on proxy-report.

Meyer, Michael; Oberhoffer, Renate; Hock, Julia; Giegerich, Tobias; Müller, Jan

doi:10.1111/jpc.13166

2016

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Title:: Health-related quality of life in children and adolescents: Current normative data, determinants and reliability on proxy-report.
Document type:: Journal Article
Author(s):: Meyer, Michael; Oberhoffer, Renate; Hock, Julia; Giegerich, Tobias; Müller, Jan
Abstract:: Health-related quality of life (HrQoL) is a multidimensional concept including self-reported measures of physical and mental health. Throughout the last decades, HrQoL has become a more and more important outcome measure not only in clinical conditions. This study evaluates current HrQoL of healthy children and adolescents, determinants of HrQoL, and the agreement between self- and proxy-report.From April 2012 to July 2013, we prospectively examined 530 healthy children (13.2 ± 2.1 years, 236 girls) and their parents on their childrens HrQoL using the KINDL-R self-report questionnaire and the parent's proxy-report. Data was compared to the established reference value from 2007 and the agreement of self- and parent's proxy-report was assessed by calculation of intraclass correlation coefficient (ICC).In general, the HrQoL improved compared to references in both children's (104.5 ± 12.6 % of predicted reference value, P < .001) and parent's proxy-report (104.3 ± 12.3 % of predicted reference value, P < .001). HrQoL declined with proceeding age (r = -.247, P < .001) but was not associated with BMI (r = -.035, P = .420). There was good accordance between children's reported HrQoL and the parent's proxy-report (ICC: .774). Only in the domains 'self-esteem' (ICC: .558) and 'Emotional well-being' (ICC: .612) the agreements were moderate.HrQoL perception has increased throughout the past 10 years and worsens with increasing age. Moreover, the parent's proxy-report of the KINDL-R questionnaire is a good supplementary method to provide additional information regarding to children's HrQoL.
Journal title abbreviation:: J Paediatr Child Health
Year:: 2016
Journal volume:: 52
Journal issue:: 6
Pages contribution:: 628-31
Language:: eng
Fulltext / DOI:: doi:10.1111/jpc.13166
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/27144733
Print-ISSN:: 1034-4810
TUM Institution:: Klinik für Kinderkardiologie und angeborene Herzfehler (Prof. Hess)
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mediaTUM Gesamtbestand Einrichtungen Schools TUM School of Medicine and Health Departments Clinical Medicine Lehr- und Forschungskooperationen mit den Kliniken und Instituten am Deutschen Herzzentrum Klinik für Kinderkardiologie und angeborene Herzfehler (DHM) (Prof. Ewert)2016