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Titel:

Platelets in atherosclerosis and thrombosis.

Dokumenttyp:
Journal Article; Review
Autor(en):
Schulz, C; Massberg, S
Abstract:
Rupture of an atherosclerotic plaque exposes a thrombogenic matrix, which instantly triggers platelet tethering and activation. We here delineate the sequence of events during arterial thrombus formation and dissect the specific role of the various platelet receptors in this process. We also discuss the interplay of platelets with circulating immune cells, which support arterial thrombosis by fibrin formation in a process that involves extracellular nucleosomes. In the second part of this chapte...     »
Zeitschriftentitel:
Handb Exp Pharmacol
Jahr:
2012
Heft / Issue:
210
Seitenangaben Beitrag:
111-33
Sprache:
eng
Volltext / DOI:
doi:10.1007/978-3-642-29423-5_5
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22918729
Print-ISSN:
0171-2004
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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