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- Title:
Strong genetic evidence for association of TOR1A/TOR1B with idiopathic dystonia.
- Document type:
- Journal Article; Research Support, Non-U.S. Gov't
- Author(s):
- Kamm, C; Asmus, F; Mueller, J; Mayer, P; Sharma, M; Muller, UJ; Beckert, S; Ehling, R; Illig, T; Wichmann, HE; Poewe, W; Mueller, JC; Gasser, T
- Abstract:
- Recently, association of a TOR1A(DYT1)/TOR1B risk haplotype with common forms of idiopathic dystonia has been reported in the Icelandic population. Here we report a strong association of two single nucleotide polymorphisms within or in close proximity to the TOR1A 3'UTR, with the lowest p value being 0.000008, in a larger cohort of German and Austrian patients with predominantly focal sporadic dystonia.
- Journal title abbreviation:
- Neurology
- Year:
- 2006
- Journal volume:
- 67
- Journal issue:
- 10
- Pages contribution:
- 1857-9
- Language:
- eng
- Fulltext / DOI:
- doi:10.1212/01.wnl.0000244423.63406.17
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/17130424
- Print-ISSN:
- 0028-3878
- TUM Institution:
- Klinik und Poliklinik für Psychiatrie und Psychotherapie
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