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- Title:
Comprehensive association analysis of the NOS2A gene with Parkinson disease.
- Document type:
- Journal Article; Research Support, Non-U.S. Gov't
- Author(s):
- Schulte, C; Sharma, M; Mueller, JC; Lichtner, P; Prestel, J; Berg, D; Gasser, T
- Abstract:
- Inducible nitric oxide synthase (NOS2A) may be involved in the oxidative stress pathology of Parkinson disease (PD). Two previous studies reported an association of a single nucleotide polymorphism (rs1060826) with PD. A replication study of 340 German patients and 680 controls showed no significant association between 12 genotyped polymorphisms and PD. NOS2A is therefore not a major susceptibility locus in our relatively young sample population.
- Journal title abbreviation:
- Neurology
- Year:
- 2006
- Journal volume:
- 67
- Journal issue:
- 11
- Pages contribution:
- 2080-2
- Language:
- eng
- Fulltext / DOI:
- doi:10.1212/01.wnl.0000247672.41736.bd
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/17159127
- Print-ISSN:
- 0028-3878
- TUM Institution:
- Klinik und Poliklinik für Psychiatrie und Psychotherapie
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