Comprehensive association analysis of the NOS2A gene with Parkinson disease.

Titel:: Comprehensive association analysis of the NOS2A gene with Parkinson disease.
Dokumenttyp:: Journal Article; Research Support, Non-U.S. Gov't
Autor(en):: Schulte, C; Sharma, M; Mueller, JC; Lichtner, P; Prestel, J; Berg, D; Gasser, T
Abstract:: Inducible nitric oxide synthase (NOS2A) may be involved in the oxidative stress pathology of Parkinson disease (PD). Two previous studies reported an association of a single nucleotide polymorphism (rs1060826) with PD. A replication study of 340 German patients and 680 controls showed no significant association between 12 genotyped polymorphisms and PD. NOS2A is therefore not a major susceptibility locus in our relatively young sample population.
Zeitschriftentitel:: Neurology
Jahr:: 2006
Band / Volume:: 67
Heft / Issue:: 11
Seitenangaben Beitrag:: 2080-2
Sprache:: eng
Volltext / DOI:: doi:10.1212/01.wnl.0000247672.41736.bd
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/17159127
Print-ISSN:: 0028-3878
TUM Einrichtung:: Klinik und Poliklinik für Psychiatrie und Psychotherapie
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