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Title:

Prediction of individual clinical outcome in MCI by means of genetic assessment and (18)F-FDG PET.

Document type:
Controlled Clinical Trial; Journal Article; Article
Author(s):
Drzezga, A; Grimmer, T; Riemenschneider, M; Lautenschlager, N; Siebner, H; Alexopoulus, P; Minoshima, S; Schwaiger, M; Kurz, A
Abstract:
Patients with mild cognitive impairment (MCI) represent a risk population for progressing to dementia of the Alzheimer type (DAT). However, clinical criteria do not ensure reliable individual prognosis in these patients. The objective of this longitudinal, prospective study was to examine the value of (18)F-FDG PET of cerebral glucose metabolism and of genetic susceptibility, as defined by an APOEepsilon4-positive genotype, with regard to the early diagnosis of DAT in patients with MCI. METHODS:...     »
Journal title abbreviation:
J Nucl Med
Year:
2005
Journal volume:
46
Journal issue:
10
Pages contribution:
1625-32
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16204712
Print-ISSN:
0161-5505
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für Psychiatrie und Psychotherapie
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