Multiple sclerosis coinciding with Machado-Joseph disease.

Title:: Multiple sclerosis coinciding with Machado-Joseph disease.
Document type:: Case Reports; Journal Article; Article
Author(s):: Röhl, JE; Lünemann, JD; Zimmer, C; Zschenderlein, R; Valdueza, JM
Abstract:: Although inflammatory demyelination is considered to be the key feature in multiple sclerosis (MS) pathogenesis, histopathological investigations and MRI studies recently highlighted the extent of neuronal damage that occurs even in the early stages of the disease. We report the unusual case of a patient with Machado-Joseph disease (MJD; spinocerebellar ataxia (SCA) III) and discuss this coincidence in light current pathogenetic paradigms of CNS autoimmunity.
Journal title abbreviation:: Neurol Sci
Year:: 2005
Journal volume:: 26
Journal issue:: 2
Pages contribution:: 135-6
Language:: eng
Fulltext / DOI:: doi:10.1007/s10072-005-0447-0
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/15995831
Print-ISSN:: 1590-1874
TUM Institution:: Fachgebiet Neuroradiologie (Prof. Zimmer)
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