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Title:

Frequency-correlated decreases of motor cortex activity associated with subthalamic nucleus stimulation in Parkinson's disease.

Document type:
Clinical Trial; Journal Article; Article
Author(s):
Haslinger, B; Kalteis, K; Boecker, H; Alesch, F; Ceballos-Baumann, AO
Abstract:
According to the classical model of basal ganglia organization, deep brain stimulation (DBS) in the subthalamic nucleus (STN) for the treatment of Parkinson's disease (PD) blocks overactive excitatory projections to inhibitory basal ganglia output structures. This would release the break on thalamofrontal neurons alleviating the poverty of movement, the hallmark of PD. Such parallels to a functional lesion certainly simplify the mechanism of STN DBS. Here, we applied parametric analyses of H2(15...     »
Journal title abbreviation:
Neuroimage
Year:
2005
Journal volume:
28
Journal issue:
3
Pages contribution:
598-606
Language:
eng
Fulltext / DOI:
doi:10.1016/j.neuroimage.2005.06.034
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16081302
Print-ISSN:
1053-8119
TUM Institution:
Neurologische Klinik und Poliklinik
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