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Titel:

[3H]-nociceptin ligand-binding and nociceptin opioid receptor mrna expression in the human brain.

Dokumenttyp:
Journal Article; Article
Autor(en):
Berthele, A; Platzer, S; Dworzak, D; Schadrack, J; Mahal, B; Büttner, A; Assmus, HP; Wurster, K; Zieglgänsberger, W; Conrad, B; Tölle, TR
Abstract:
Following the cloning of the novel nociceptin opioid receptor (NOP(1)) and the identification of its endogenous ligand orphanin FQ/nociceptin the distribution and functional role of the NOP(1) receptor system have been studied mainly in the rodent CNS. In the present study the regional distribution and splice variant expression of the NOP(1) receptor was investigated in the adult human brain using [(3)H]-nociceptin autoradiography, NOP(1) reverse transcriptase PCR and mRNA in situ hybridization....     »
Zeitschriftentitel:
Neuroscience
Jahr:
2003
Band / Volume:
121
Heft / Issue:
3
Seitenangaben Beitrag:
629-40
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/14568023
Print-ISSN:
0306-4522
TUM Einrichtung:
Neurologische Klinik und Poliklinik
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