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Title:

Cerebral iron oxide distribution: in vivo mapping with MR imaging.

Document type:
Journal Article; Article
Author(s):
Zimmer, C; Weissleder, R; O'Connor, D; LaPointe, L; Brady, TJ; Enochs, WS
Abstract:
PURPOSE: To map the distribution of an iron oxide label in the central nervous system with in vivo magnetic resonance (MR) imaging. MATERIALS AND METHODS: Unilateral osmotic disruption of the blood-brain barrier (BBB) in rats (n = 40) was followed by injection of monocrystalline iron oxide nanoparticles (MION) into the carotid artery. MR images (1.5 T) were obtained in and ex vivo, and results were correlated with histologic section-matched iron maps. RESULTS: A mean of 0.2% of the injected MION...     »
Journal title abbreviation:
Radiology
Year:
1995
Journal volume:
196
Journal issue:
2
Pages contribution:
521-7
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/7617871
Print-ISSN:
0033-8419
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer)
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