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Titel:

Lactacidosis-induced glial cell swelling depends on extracellular Ca2+.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Ringel, F; Baethmann, A; Plesnila, N
Abstract:
Cerebral tissue acidosis following ischemia or traumatic brain injury contributes to cytotoxic brain edema formation. In vitro lactacidosis induces swelling of glial cells by intracellular Na+- and Cl--accumulation by the Na+/H+-antiporter, Cl-/HCO3--antiporters and the Na+-K+-2Cl--cotransport. The present study aimed to elucidate whether mechanisms of lactacidosis-induced glial swelling are dependent on intra- or extracellular Ca2+-ions. Therefore, C6 glioma cells were exposed to a lactacidosis...     »
Zeitschriftentitel:
Neurosci Lett
Jahr:
2006
Band / Volume:
398
Heft / Issue:
3
Seitenangaben Beitrag:
306-9
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.neulet.2006.01.012
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16469448
Print-ISSN:
0304-3940
TUM Einrichtung:
Neurochirurgische Klinik und Poliklinik
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