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Titel:

Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics.

Dokumenttyp:
Journal Article
Autor(en):
Achenbach, P; Warncke, K; Reiter, J; Naserke, HE; Williams, AJ; Bingley, PJ; Bonifacio, E; Ziegler, AG
Abstract:
Family history of type 1 diabetes and autoantibodies to the islet antigens insulin (IAA), glutamate decarboxylase (GADA), and the protein tyrosine phosphatase-like protein IA-2 (IA-2A) are strong predictors of type 1 diabetes, but the rate of progression to diabetes in multiple islet autoantibody-positive relatives varies widely. We asked whether detailed characterization of islet autoantibodies that included determination of titer, epitope specificity, and IgG subclass would improve diabetes pr...     »
Zeitschriftentitel:
Diabetes
Jahr:
2004
Band / Volume:
53
Heft / Issue:
2
Seitenangaben Beitrag:
384-92
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/14747289
Print-ISSN:
0012-1797
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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