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Titel:

Tyrosine site-specific recombinases mediate DNA inversions affecting the expression of outer surface proteins of Bacteroides fragilis.

Dokumenttyp:
Journal Article
Autor(en):
Weinacht, KG; Roché, H; Krinos, CM; Coyne, MJ; Parkhill, J; Comstock, LE
Abstract:
The chromosome of Bacteroides fragilis has been shown to undergo 13 distinct DNA inversions affecting the expression of capsular polysaccharides and mediated by a serine site-specific recombinase designated Mpi. In this study, we demonstrate that members of the tyrosine site-specific recombinase family, conserved in B. fragilis, mediate additional DNA inversions of the B. fragilis genome. These DNA invertases flip promoter regions in their immediate downstream region. The genetic organization of...     »
Zeitschriftentitel:
Mol Microbiol
Jahr:
2004
Band / Volume:
53
Heft / Issue:
5
Seitenangaben Beitrag:
1319-30
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1365-2958.2004.04219.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15387812
Print-ISSN:
0950-382X
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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