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Titel:

Exogenously added GPI-anchored tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) displays enhanced and novel biological activities.

Dokumenttyp:
Journal Article
Autor(en):
Djafarzadeh, R; Mojaat, A; Vicente, AB; von Lüttichau, I; Nelson, PJ
Abstract:
The family of tissue inhibitors of metalloproteinases (TIMPs) exhibits diverse physiological/biological functions including the inhibition of active matrix metalloproteinases, regulation of proMMP activation, cell growth, and the modulation of angiogenesis. TIMP-1 is a secreted protein that can be detected on the cell surface through its interaction with surface proteins. The diverse biological functions of TIMP-1 are thought to lie, in part, in the kinetics of TIMP-1/MMP/surface protein interac...     »
Zeitschriftentitel:
Biol Chem
Jahr:
2004
Band / Volume:
385
Heft / Issue:
7
Seitenangaben Beitrag:
655-63
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15318815
Print-ISSN:
1431-6730
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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