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Titel:

T cell recognition of bcr/abl in healthy donors and in patients with chronic myeloid leukaemia.

Dokumenttyp:
Journal Article
Autor(en):
Westermann, J; Schlimper, C; Richter, G; Mohm, J; Dörken, B; Pezzutto, A
Abstract:
In chronic myeloid leukaemia (CML), peptides from the fusion region of bcr3/abl2 are likely to play a role in anti-leukaemic T cell immunity. We investigated whether T cells that recognize bcr/abl fusion peptides could be detected in healthy donors and CML patients. T cell responses against bcr3/abl2 fusion peptides were analysed by gamma-interferon enzyme-linked immunospot assays after prestimulation of peripheral blood mononuclear cells in the presence of anti-CD3-antibodies and interleukin-2....     »
Zeitschriftentitel:
Br J Haematol
Jahr:
2004
Band / Volume:
125
Heft / Issue:
2
Seitenangaben Beitrag:
213-6
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1365-2141.2004.04873.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15059144
Print-ISSN:
0007-1048
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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