User: Guest  Login
More Searchfields
Simple search
Title:

Treatment of Crigler-Najjar type 1 disease: relevance of early liver transplantation.

Document type:
Journal Article; Article
Author(s):
Schauer, R; Stangl, M; Lang, T; Zimmermann, A; Chouker, A; Gerbes, AL; Schildberg, FW; Rau, HG
Abstract:
BACKGROUND: Crigler-Najjar syndrome type 1 (CNS1) is characterized by severe unconjugated hyperbilirubinemia from birth, caused by total failure of UDP-glucuronyltransferase activity. Only orthotopic liver transplantation (OLT) offers the prospect of cure. However, because the onset of neurologic deficits is unpredictable, timing of OLT remains difficult. METHODS: In our transplant center, 3 patients underwent early OLT for CNS1. Two of them (7 yr, 12 yr) showed mild to moderate neurologic defic...     »
Journal title abbreviation:
J Pediatr Surg
Year:
2003
Journal volume:
38
Journal issue:
8
Pages contribution:
1227-31
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12891498
Print-ISSN:
0022-3468
TUM Institution:
Fachgebiet Perinatalmedizin und Perinatalphysiologie (Prof. Schneider)
 BibTeX