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Title:

Various 'dendritic cell antigens' are already expressed on uncultured blasts in acute myeloid leukemia and myelodysplastic syndromes.

Document type:
Journal Article
Author(s):
Dreyssig, J; Kremser, A; Liepert, A; Grabrucker, C; Freudenreich, M; Schmid, C; Kroell, T; Schöll, N; Tischer, J; Kufner, S; Salih, H; Kolb, HJ; Schmetzer, HM
Abstract:
Leukemia-derived dendritic cells (DC(leu)) potentially present the whole leukemic antigen repertoire. We studied antigen-expression profiles of blasts/dendritic cells (DCs) generated from 137 acute myeloid leukemia (AML)/49 myelodysplastic syndromes (MDS) patients with six different DC-generating media by flow-cytometry combining expression of blast/maturation and DC antigens (DCA:CD1a,b,c, CD25, CD40, CD80, CD83, CD86, CD137-L and CD206).First, DCA are regularly and variably expressed on uncult...     »
Journal title abbreviation:
Immunotherapy
Year:
2011
Journal volume:
3
Journal issue:
9
Pages contribution:
1113-24
Language:
eng
Fulltext / DOI:
doi:10.2217/imt.11.108
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21913833
Print-ISSN:
1750-743X
TUM Institution:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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