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Title:

Association of transforming growth factor-beta1 gene polymorphisms with myocardial infarction in patients with angiographically proven coronary heart disease.

Document type:
Journal Article; Article
Author(s):
Koch, W; Hoppmann, P; Mueller, JC; Schömig, A; Kastrati, A
Abstract:
OBJECTIVE: Transforming growth factor (TGF)-beta1 (TGF-beta1) is a multifunctional cytokine that exhibits vasculoprotective properties. Production and plasma levels of TGF-beta1 are influenced by polymorphisms in the TGF-beta1 gene (TGFB1). We investigated whether the -509C/T (rs1800469), 868T/C (rs1982073), 913G/C (rs1800471), and 11929C/T (rs1800472) polymorphisms of TGFB1 are associated with myocardial infarction. METHODS AND RESULTS: The study population consisted of 3657 patients with myoca...     »
Journal title abbreviation:
Arterioscler Thromb Vasc Biol
Year:
2006
Journal volume:
26
Journal issue:
5
Pages contribution:
1114-9
Language:
eng
Fulltext / DOI:
doi:10.1161/01.ATV.0000217747.66517.11
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16543493
Print-ISSN:
1079-5642
TUM Institution:
I. Medizinische Klinik und Poliklinik (Kardiologie); Klinik und Poliklinik für Psychiatrie und Psychotherapie
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