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Titel:

A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo.

Dokumenttyp:
Journal Article; Article
Autor(en):
Massberg, S; Gawaz, M; Grüner, S; Schulte, V; Konrad, I; Zohlnhofer, D; Heinzmann, U; Nieswandt, B
Abstract:
Platelet adhesion and aggregation at sites of vascular injury is crucial for hemostasis but may lead to arterial occlusion in the setting of atherosclerosis and precipitate diseases such as myocardial infarction. A current hypothesis suggests that platelet glycoprotein (GP) Ib interaction with von Willebrand factor recruits flowing platelets to the injured vessel wall, where subendothelial fibrillar collagens support their firm adhesion and activation. However, so far this hypothesis has not bee...     »
Zeitschriftentitel:
J Exp Med
Jahr:
2003
Band / Volume:
197
Heft / Issue:
1
Seitenangaben Beitrag:
41-9
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/12515812
Print-ISSN:
0022-1007
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie)
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