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Dokumenttyp:
Journal Article; Article
Autor(en):
von Beckerath, N; Schusterschitz, Y; Koch, W; Griesser, K; Mehilli, J; Gorchakova, O; Schömig, A; Kastrati, A
Titel:
G protein beta 3 subunit 825T allele carriage and risk of coronary artery disease.
Abstract:
C825T polymorphism in the G protein beta3 subunit gene (GNB3) is associated with increased transmembrane signal transduction via adenylyl cyclase inhibiting G (G(i)) proteins. We tested whether GNB3 C825T is associated with an increased risk of coronary artery disease (CAD). Genotypes were determined with polymerase chain reaction and allele-specific fluorogenic probes. Angiographically examined, consecutive patients (n=998) with CAD and angiographically examined, sex- and age-matched controls (...     »
Zeitschriftentitel:
Atherosclerosis
Jahr:
2003
Band / Volume:
167
Heft / Issue:
1
Seitenangaben Beitrag:
135-9
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/12618278
Print-ISSN:
0021-9150
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie)
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