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Titel:

The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Adam, AC; Bornhövd, C; Prokisch, H; Neupert, W; Hell, K
Abstract:
Formation of iron/sulfur (Fe/S) clusters, protein translocation and protein folding are essential processes in the mitochondria of Saccharomyces cerevisiae. In a systematic approach to characterize essential proteins involved in these processes, we identified a novel essential protein of the mitochondrial matrix, which is highly conserved from yeast to human and which we termed Isd11. Depletion of Isd11 caused a strong reduction in the levels of the Fe/S proteins aconitase and the Rieske protein...     »
Zeitschriftentitel:
EMBO J
Jahr:
2006
Band / Volume:
25
Heft / Issue:
1
Seitenangaben Beitrag:
174-83
Sprache:
eng
Volltext / DOI:
doi:10.1038/sj.emboj.7600905
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16341090
Print-ISSN:
0261-4189
TUM Einrichtung:
Institut für Humangenetik
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