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Title:

Assessing systems properties of yeast mitochondria through an interaction map of the organelle.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Perocchi, F; Jensen, LJ; Gagneur, J; Ahting, U; von Mering, C; Bork, P; Prokisch, H; Steinmetz, LM
Abstract:
Mitochondria carry out specialized functions; compartmentalized, yet integrated into the metabolic and signaling processes of the cell. Although many mitochondrial proteins have been identified, understanding their functional interrelationships has been a challenge. Here we construct a comprehensive network of the mitochondrial system. We integrated genome-wide datasets to generate an accurate and inclusive mitochondrial parts list. Together with benchmarked measures of protein interactions, a...     »
Journal title abbreviation:
PLoS Genet
Year:
2006
Journal volume:
2
Journal issue:
10
Pages contribution:
e170
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pgen.0020170
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17054397
Print-ISSN:
1553-7390
TUM Institution:
Institut für Humangenetik
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