User: Guest  Login
More Searchfields
Simple search
Title:

Multiple regions of alpha-synuclein are associated with Parkinson's disease.

Document type:
Journal Article; Article
Author(s):
Mueller, JC; Fuchs, J; Hofer, A; Zimprich, A; Lichtner, P; Illig, T; Berg, D; Wüllner, U; Meitinger, T; Gasser, T
Abstract:
alpha-Synuclein is considered to play an important role in the pathogenesis of both the rare familial and the common sporadic forms of Parkinson's disease. Previous reports primarily have tested the association of alpha-synuclein promoter polymorphisms with idiopathic Parkinson's disease, but results are controversial. We first characterized the linkage disequilibrium structure of the alpha-synuclein gene region with a dense set of 56 genetic markers and subsequently performed two independent ca...     »
Journal title abbreviation:
Ann Neurol
Year:
2005
Journal volume:
57
Journal issue:
4
Pages contribution:
535-41
Language:
eng
Fulltext / DOI:
doi:10.1002/ana.20438
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15786467
Print-ISSN:
0364-5134
TUM Institution:
Institut für Humangenetik
 BibTeX