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Titel:

Functional profiling of human atrial and ventricular gene expression.

Dokumenttyp:
Journal Article; Validation Studies; Article
Autor(en):
Barth, AS; Merk, S; Arnoldi, E; Zwermann, L; Kloos, P; Gebauer, M; Steinmeyer, K; Bleich, M; Kääb, S; Pfeufer, A; Uberfuhr, P; Dugas, M; Steinbeck, G; Näbauer, M
Abstract:
The purpose of our investigation was to identify the transcriptional basis for ultrastructural and functional specialization of human atria and ventricles. Using exploratory microarray analysis (Affymetrix U133A+B), we detected 11,740 transcripts expressed in human heart, representing the most comprehensive report of the human myocardial transcriptome to date. Variation in gene expression between atria and ventricles accounted for the largest differences in this data set, as 3.300 and 2.974 tran...     »
Zeitschriftentitel:
Pflugers Arch
Jahr:
2005
Band / Volume:
450
Heft / Issue:
4
Seitenangaben Beitrag:
201-8
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00424-005-1404-8
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15877233
Print-ISSN:
0031-6768
TUM Einrichtung:
Institut für Humangenetik
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