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Titel:

Characterization of all human male synaptonemal complexes by subtelomere multiplex-FISH.

Dokumenttyp:
Journal Article; Article
Autor(en):
Codina-Pascual, M; Kraus, J; Speicher, MR; Oliver-Bonet, M; Murcia, V; Sarquella, J; Egozcue, J; Navarro, J; Benet, J
Abstract:
During meiotic prophase I, homologous chromosomes synapse and recombine. Both events are of vital importance for the success of meiosis. When homologous chromosomes synapse, a proteinaceous structure called synaptonemal complex (SC) appears along the pairing axis and meiotic recombination takes place. The existence of immunolabeling techniques for SC proteins (SCP1, SCP2 and SCP3) and for DNA mismatch repair proteins present in late recombination nodules (MLH1) allow analyses of both synapsis an...     »
Zeitschriftentitel:
Cytogenet Genome Res
Jahr:
2004
Band / Volume:
107
Heft / Issue:
1-2
Seitenangaben Beitrag:
18-21
Sprache:
eng
Volltext / DOI:
doi:10.1159/000079566
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15305051
Print-ISSN:
1424-8581
TUM Einrichtung:
Institut für Humangenetik
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