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Titel:

Apical membrane P2Y4 purinergic receptor controls K+ secretion by strial marginal cell epithelium.

Dokumenttyp:
Journal Article
Autor(en):
Marcus, DC; Liu, J; Lee, JH; Scherer, EQ; Scofield, MA; Wangemann, P
Abstract:
BACKGROUND: It was previously shown that K+ secretion by strial marginal cell epithelium is under the control of G-protein coupled receptors of the P2Y family in the apical membrane. Receptor activation by uracil nucleotides (P2Y2, P2Y4 or P2Y6) leads to a decrease in the electrogenic K+ secretion. The present study was conducted to determine the subtype of the functional purinergic receptor in gerbil stria vascularis, to test if receptor activation leads to elevation of intracellular [Ca2+] and...     »
Zeitschriftentitel:
Cell Commun Signal
Jahr:
2005
Band / Volume:
3
Seitenangaben Beitrag:
13
Sprache:
eng
Volltext / DOI:
doi:10.1186/1478-811X-3-13
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16266433
Print-ISSN:
1478-811X
TUM Einrichtung:
Hals-Nasen-Ohrenklinik und Poliklinik
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