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Titel:

Toll-like receptor 4 gene polymorphisms and myocardial infarction: no association in a Caucasian population.

Dokumenttyp:
Journal Article; Article
Autor(en):
Koch, W; Hoppmann, P; Pfeufer, A; Schömig, A; Kastrati, A
Abstract:
AIMS: The toll-like receptor 4 (TLR4) is predominantly known for its role as an important mediator of immune reactions and has been implicated in the initiation, progression, and plaque destabilization stages of atherosclerosis. We investigated whether genotypes and haplotypes of the 896A/G (Asp299Gly; rs4986790) and 1196C/T (Thr399Ile; rs4986791) single nucleotide polymorphisms of the gene encoding the TLR4 were associated with myocardial infarction (MI) in a large Caucasian sample. METHODS A...     »
Zeitschriftentitel:
Eur Heart J
Jahr:
2006
Band / Volume:
27
Heft / Issue:
21
Seitenangaben Beitrag:
2524-9
Sprache:
eng
Volltext / DOI:
doi:10.1093/eurheartj/ehl231
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16954131
Print-ISSN:
0195-668X
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie)
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