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Title:

Intercellular adhesion molecule-1 blockade attenuates inflammatory response and improves microvascular perfusion in rat pancreas grafts.

Document type:
Journal Article
Author(s):
Preissler, G; Eichhorn, M; Waldner, H; Winter, H; Kleespies, A; Massberg, S
Abstract:
After pancreas transplantation (PTx), early capillary malperfusion and leukocyte recruitment indicate the manifestation of severe ischemia/reperfusion injury (IRI). Oscillatory blood-flow redistribution (intermittent capillary perfusion, IP), leading to an overall decrease in erythrocyte flux, precedes complete microvascular perfusion failure with persistent blood flow cessation. We addressed the role of intercellular adhesion molecule-1 (ICAM-1) for leukocyte-endothelial interactions (LEIs) aft...     »
Journal title abbreviation:
Pancreas
Year:
2012
Journal volume:
41
Journal issue:
7
Pages contribution:
1112-8
Language:
eng
Fulltext / DOI:
doi:10.1097/MPA.0b013e31824abb2c
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22617707
Print-ISSN:
0885-3177
TUM Institution:
Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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