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Titel:

[Translational research in renal cell cancer. Illustrated by the example of the vascular endothelial growth factor pathway]

Dokumenttyp:
English Abstract; Journal Article; Article
Autor(en):
Kuefer, R; Autenrieth, M; Herkommer, K; Blum, P; Merseburger, A; Hofer, M; Rinnab, L; Gschwend, J; Ringhoffer, M
Abstract:
For patients with metastatic renal cell cancer (RCC), therapeutic options after cytokine failure are rather limited. There is a considerable need to identify new substances for systemic therapy. Due to upregulation after the loss of a functional von Hippel Lindau gene product, the vascular endothelial growth factor (VEGF) pathway is a promising target for a molecular based therapy. Over the last few years, therapeutic agents have been developed which inhibit this pathway at various levels. Here,...     »
Zeitschriftentitel:
Urologe A
Jahr:
2006
Band / Volume:
45
Heft / Issue:
3
Seitenangaben Beitrag:
328, 330-5
Sprache:
de
Volltext / DOI:
doi:10.1007/s00120-006-1006-x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16465522
Print-ISSN:
0340-2592
TUM Einrichtung:
Urologische Klinik und Poliklinik
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