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Title:

Germline mutations of the MSR1 gene in prostate cancer families from Germany.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Author(s):
Maier, C; Vesovic, Z; Bachmann, N; Herkommer, K; Braun, AK; Surowy, HM; Assum, G; Paiss, T; Vogel, W
Abstract:
The MSR1 gene at 8p22 has been suggested as a candidate gene for hereditary prostate cancer because germline variants have been found to be associated with the disease. Aside from a single nonsense mutation (R293X) that was found repeatedly at low frequencies in several samples, little evidence has been gained by follow-up studies to confirm the gene's relevance for prostate cancer. Prompted by reasonable support for a linkage to 8p22, we sought to determine the mutation spectrum of MSR1 in our...     »
Journal title abbreviation:
Hum Mutat
Year:
2006
Journal volume:
27
Journal issue:
1
Pages contribution:
98-102
Language:
eng
Fulltext / DOI:
doi:10.1002/humu.20271
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16287155
Print-ISSN:
1059-7794
TUM Institution:
Urologische Klinik und Poliklinik
 BibTeX