User: Guest  Login
More Searchfields
Simple search
Title:

Role of the Nijmegen breakage syndrome 1 gene in familial and sporadic prostate cancer.

Document type:
Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Author(s):
Hebbring, SJ; Fredriksson, H; White, KA; Maier, C; Ewing, C; McDonnell, SK; Jacobsen, SJ; Cerhan, J; Schaid, DJ; Ikonen, T; Autio, V; Tammela, TL; Herkommer, K; Paiss, T; Vogel, W; Gielzak, M; Sauvageot, J; Schleutker, J; Cooney, KA; Isaacs, W; Thibodeau, SN
Abstract:
The Nijmegen breakage syndrome 1 (NBS1) gene, which participates in DNA double strand break repair, has been postulated to be a susceptibility factor for a number of cancers, including prostate cancer. Numerous mutations have been identified in NBS1, including the founder mutation 657del5. In this study, a number of analyses were done to determine whether mutations in NBS1 are associated with an increased risk for prostate cancer. The frequency of the 657del5 mutation in both familial prostate c...     »
Journal title abbreviation:
Cancer Epidemiol Biomarkers Prev
Year:
2006
Journal volume:
15
Journal issue:
5
Pages contribution:
935-8
Language:
eng
Fulltext / DOI:
doi:10.1158/1055-9965.EPI-05-0910
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16702373
Print-ISSN:
1055-9965
TUM Institution:
Urologische Klinik und Poliklinik
 BibTeX