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Titel:

CXCR4 expression reflects tumor progression and regulates motility of bladder cancer cells.

Dokumenttyp:
Journal Article; Article
Autor(en):
Retz, MM; Sidhu, SS; Blaveri, E; Kerr, SC; Dolganov, GM; Lehmann, J; Carroll, P; Simko, J; Waldman, FM; Basbaum, C
Abstract:
Transitional cell carcinoma of the urinary bladder remains life threatening due to the high occurrence of metastases. Emerging evidence suggests that chemokines and their receptors play a critical role in tumor metastases. In our study, we performed a systematic analysis of the mRNA and protein expression levels of all 18 chemokine receptors in normal urothelium and bladder cancer. CXCR4 was the only chemokine receptor whose mRNA expression level was upregulated in bladder cancer cell lines as w...     »
Zeitschriftentitel:
Int J Cancer
Jahr:
2005
Band / Volume:
114
Heft / Issue:
2
Seitenangaben Beitrag:
182-9
Sprache:
eng
Volltext / DOI:
doi:10.1002/ijc.20729
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15540205
Print-ISSN:
0020-7136
TUM Einrichtung:
Urologische Klinik und Poliklinik
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