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Title:

Coxsackieviral replication and pathogenicity: lessons from gene modified animal models.

Document type:
Journal Article; Review; Review
Author(s):
Wessely, R
Abstract:
Coxsackieviruses have been implicated in the pathogenesis of human myocarditis and some forms of dilated cardiomyopathy. A considerable portion of our knowledge about the pathophysiology of viral heart disease is derived from animal studies. In particular, investigations utilising gene-targeted mice provide valuable new insights into various aspects of viral pathogenicity and host factors involved in the control of viral replication. This review focuses on models in cell culture and transgenic a...     »
Journal title abbreviation:
Med Microbiol Immunol (Berl)
Year:
2004
Journal volume:
193
Journal issue:
2-3
Pages contribution:
71-4
Language:
eng
Fulltext / DOI:
doi:10.1007/s00430-003-0203-0
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/14579153
Print-ISSN:
0300-8584
TUM Institution:
I. Medizinische Klinik und Poliklinik (Kardiologie)
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