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- Titel:
Influence of transrectal ultrasound probe on prostate cancer detection in transrectal ultrasound-guided sextant biopsy of prostate.
- Dokumenttyp:
- Evaluation Studies; Journal Article; Multicenter Study; Article
- Autor(en):
- Paul, R; Korzinek, C; Necknig, U; Niesel, T; Alschibaja, M; Leyh, H; Hartung, R
- Abstract:
- OBJECTIVES: To determine whether end-fire probes increase the prostate cancer (PCa) detection rate. Enhancing the PCa detection rate is the main goal of biopsy protocols. Prostate biopsy is limited by side-fire probes to a longitudinal axis, but end-fire probes allow biopsy cores to also be taken in the transverse section. METHODS: A total of 2625 patients underwent systematic sextant biopsy in three institutions using the same protocol. Three different ultrasound probes were used-the Kretz Combisone and Bruel & Kjaer side-fire probes and the ATL HDI end-fire probe. We retrospectively evaluated the influence of the probe on the PCa detection rate. RESULTS: The Kretz probe was used in 384 men, the Bruel & Kjaer probe in 598 men, and the ATL probe in 1643 men. Overall, 35.2% had PCa detected. Analyzing all patients, no statistically significant difference (P = 0.73) was found for the probes, but the subgroup with a prostate-specific antigen level of 4 to 10 ng/mL demonstrated a statistically significant improvement in the detection rate using the end-fire probe (31.3% versus 24.5% and 21.5% for the side-fire probes, P = 0.01). Patients with nonpalpable PCa also demonstrated a statistically significant increase in detection with the end-fire probe (P = 0.004). Multivariate analysis confirmed that the ultrasound probe is an independent parameter to enhance the PCa detection rate. CONCLUSIONS: Our results showed that end-fire probes provide a statistically significant improvement in the PCa detection rate compared with side-fire probes in patients with a prostate-specific antigen level of 4 to 10 ng/mL and nonpalpable disease. The reason could be the facilitated sampling in the most lateral part of the peripheral zone. Our results suggest that the widespread use of end-fire probes for prostate biopsy could enhance the PCa detection rate.
- Zeitschriftentitel:
- Urology
- Jahr:
- 2004
- Band / Volume:
- 64
- Heft / Issue:
- 3
- Seitenangaben Beitrag:
- 532-6
- Sprache:
- eng
- Volltext / DOI:
- doi:10.1016/j.urology.2004.04.005
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/15351585
- Print-ISSN:
- 0090-4295
- TUM Einrichtung:
- Urologische Klinik und Poliklinik
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