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Title:

Transcutaneous IL-2 uptake mediated by Transfersomes depends on concentration and fractionated application.

Document type:
Journal Article; Article
Author(s):
Hofer, C; van Randenborgh, H; Lehmer, A; Hartung, R; Breul, J
Abstract:
INTRODUCTION: Transfersomes (TF) are new, ultradeformable carriers with characteristics that enable them to penetrate the skin spontaneously. TFs are able to transport noninvasively both low- and high-molecular-weight molecules into the body. MATERIALS AND METHODS: TFs contain phosphatidylcholine and sodium cholate. Recombinant human interleukin-2 (Proleukin, Chiron) was added to the TFs and incubated for 24 h at 4 degrees C. The immunotransfersomes (ITF) were isolated from free interleukin-2 (I...     »
Journal title abbreviation:
Cytokine
Year:
2004
Journal volume:
25
Journal issue:
4
Pages contribution:
141-6
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15162830
Print-ISSN:
1043-4666
TUM Institution:
Urologische Klinik und Poliklinik
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