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Titel:

Characterization of osteosarcoma cell lines MG-63, Saos-2 and U-2 OS in comparison to human osteoblasts.

Dokumenttyp:
Journal Article; Article
Autor(en):
Pautke, C; Schieker, M; Tischer, T; Kolk, A; Neth, P; Mutschler, W; Milz, S
Abstract:
BACKGROUND: Osteosarcomas are malignant bone tumors consisting of cells with abnormal cellular functions. Although osteosarcoma-derived cells are commonly used for osteoblastic models, the molecular composition of the osteosarcoma extracellular matrix (ECM) is not well characterized. MATERIALS AND METHODS: We compared three osteosarcoma cell lines (MG-63, Saos-2 and U-2 OS) with normal human osteoblasts by immunocytochemistry. Cellular characteristics were assessed by morphometric analysis and p...     »
Zeitschriftentitel:
Anticancer Res
Jahr:
2004
Band / Volume:
24
Heft / Issue:
6
Seitenangaben Beitrag:
3743-8
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15736406
Print-ISSN:
0250-7005
TUM Einrichtung:
Fachgebiet Sportorthopädie (Prof. Imhoff); Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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