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Title:

[3D-Culturing of human osteoblastic cells with vessel like nutrient supply]

Document type:
Festschrift; Journal Article; Article
Author(s):
Tischer, T; Schieker, M; Stengele, M; Pautke, C; Neth, P; Jochum, M; Mutschler, W; Milz, S
Abstract:
AIM: The treatment of large, critical-size bone defects is a major therapeutic problem in orthopaedic and reconstructive surgery. The engineering of bone tissue could be used to replace lost bone mass. However, scaffolds seeded with vital cells and cultured in vitro suffer from poor oxygen and nutrient supply centrally, when the constructs exceed a critical volume. Therefore, we have established an osteoblastic cell culture in a new 3D-culture chamber with an artificial, vessel-like central memb...     »
Journal title abbreviation:
Z Orthop Ihre Grenzgeb
Year:
2004
Journal volume:
142
Journal issue:
3
Pages contribution:
344-9
Language:
de
Fulltext / DOI:
doi:10.1055/s-2004-822817
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15250009
Print-ISSN:
0044-3220
TUM Institution:
Fachgebiet Sportorthopädie (Prof. Imhoff); Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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