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Titel:

Nonviral vector loaded collagen sponges for sustained gene delivery in vitro and in vivo.

Dokumenttyp:
Journal Article
Autor(en):
Scherer, F; Schillinger, U; Putz, U; Stemberger, A; Plank, C
Abstract:
BACKGROUND: Naked DNA and standard vectors have previously been used for gene delivery from implantable carrier matrices with great potential for gene therapeutic assistance of wound healing or tissue engineering. We have previously developed copolymer-protected gene vectors which are inert towards opsonization. Here we examine their potency in carrier-mediated gene delivery in comparison to standard vectors using a vector-loaded collagen sponge model. METHODS: Equine collagen type I sponges wer...     »
Zeitschriftentitel:
J Gene Med
Jahr:
2002
Band / Volume:
4
Heft / Issue:
6
Seitenangaben Beitrag:
634-43
Sprache:
eng
Volltext / DOI:
doi:10.1002/jgm.298
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/12439855
Print-ISSN:
1099-498X
TUM Einrichtung:
Institut für Experimentelle Onkologie und Therapieforschung
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