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Title:

Nonviral vector loaded collagen sponges for sustained gene delivery in vitro and in vivo.

Document type:
Journal Article
Author(s):
Scherer, F; Schillinger, U; Putz, U; Stemberger, A; Plank, C
Abstract:
BACKGROUND: Naked DNA and standard vectors have previously been used for gene delivery from implantable carrier matrices with great potential for gene therapeutic assistance of wound healing or tissue engineering. We have previously developed copolymer-protected gene vectors which are inert towards opsonization. Here we examine their potency in carrier-mediated gene delivery in comparison to standard vectors using a vector-loaded collagen sponge model. METHODS: Equine collagen type I sponges wer...     »
Journal title abbreviation:
J Gene Med
Year:
2002
Journal volume:
4
Journal issue:
6
Pages contribution:
634-43
Language:
eng
Fulltext / DOI:
doi:10.1002/jgm.298
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12439855
Print-ISSN:
1099-498X
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung
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