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Title:

Involvement of a cGMP-dependent pathway in the natriuretic peptide-mediated hormone-sensitive lipase phosphorylation in human adipocytes.

Document type:
Journal Article; Article
Author(s):
Sengenes, C; Bouloumie, A; Hauner, H; Berlan, M; Busse, R; Lafontan, M; Galitzky, J
Abstract:
Our previous studies have demonstrated that natriuretic peptides (NPs), peptide hormones with natriuretic, diuretic, and vasodilating properties, exert a potent control on the lipolysis in human adipocytes via the activation of the type A guanylyl cyclase receptor (1, 2). In the current study we investigated the intracellular mechanisms involved in the NP-stimulated lipolytic effect in human preadipocytes and adipocytes. We demonstrate that the atrial NP (ANP)-induced lipolysis in human adipocyt...     »
Journal title abbreviation:
J Biol Chem
Year:
2003
Journal volume:
278
Journal issue:
49
Pages contribution:
48617-26
Language:
eng
Fulltext / DOI:
doi:10.1074/jbc.M303713200
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12970365
Print-ISSN:
0021-9258
TUM Institution:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin
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