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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Stalder, JF; Barbarot, S; Wollenberg, A; Holm, EA; De Raeve, L; Seidenari, S; Oranje, A; Deleuran, M; Cambazard, F; Svensson, A; Simon, D; Benfeldt, E; Reunala, T; Mazereeuv, J; Boralevi, F; Kunz, B; Misery, L; Mortz, CG; Darsow, U; Gelmetti, C; Diepgen, T; Ring, J; Moehrenschlager, M; Gieler, U; Taïeb, A
Title:
Patient-Oriented SCORAD (PO-SCORAD): a new self-assessment scale in atopic dermatitis validated in Europe.
Abstract:
BACKGROund: Patient-oriented medicine is an emerging concept, encouraged by the World Health Organization, to greater involvement of the patient in the management of chronic diseases. The Patient-Oriented SCORing Atopic Dermatitis (PO-SCORAD) index is a self-assessment score allowing the patient to comprehensively evaluate the actual course of atopic dermatitis (AD), using subjective and objective criteria derived mainly from the SCORAD, a validated AD severity clinical assessment tool.To validate the PO-SCORAD index in a large European population of patients exhibiting all forms of AD severity by assessing its correlation with the SCORAD index.Four hundred and seventy-one patients (185 adults, 286 children) consulting for AD in hospitals from 9 European countries were recruited. The investigators and the patients used the SCORAD and PO-SCORAD scales, respectively, to assess AD severity at inclusion (D0) and 28 ± 7 days later (D28).Patient-Oriented SCORing Atopic Dermatitis and SCORAD scores were significantly correlated at D0 [r = 0.67 (95% CI: 0.62; 0.72), P < 0.0001]. Consistency was confirmed at D28, with a stronger linear correlation between both scales [r = 0.79 (95% CI: 0.75; 0.83), P < 0.0001]. Absolute changes from baseline in SCORAD and PO-SCORAD scores were also significantly correlated [r= 0.71 (95% CI: 0.64; 0.76), P < 0.0001]. Although no specific intervention was investigated, AD improved over the study, with a decrease of PO-SCORAD and SCORAD scores from D0 to D28 by -19.19% and -24.39%, respectively. The consistency of the correlations was similar in the adult and children groups.This study validated the use of PO-SCORAD to self-assess AD severity and demonstrated its good correlation with SCORAD.
Journal title abbreviation:
Allergy
Year:
2011
Journal volume:
66
Journal issue:
8
Pages contribution:
1114-21
Language:
eng
Fulltext / DOI:
doi:10.1111/j.1398-9995.2011.02577.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21414011
Print-ISSN:
0105-4538
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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