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Title:

Transforming growth factor-beta: recent advances on its role in immune tolerance.

Document type:
Journal Article
Author(s):
Mantel, PY; Schmidt-Weber, CB
Abstract:
Transforming growth factor (TGF-?1) is a pleiotropic cytokine, secreted by immune and nonhematopoietic cells. TGF-? is involved in many different critical processes, such as embryonal development, cellular maturation and differentiation, wound healing, and immune regulation. It maintains immune homeostasis by acting as a potent immune suppressor through inhibition of proliferation, differentiation, activation, and effector function of immune cells. Paradoxically, depending on the context, it dis...     »
Journal title abbreviation:
Methods Mol Biol
Year:
2011
Journal volume:
677
Pages contribution:
303-38
Language:
eng
Fulltext / DOI:
doi:10.1007/978-1-60761-869-0_21
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20941619
Print-ISSN:
1064-3745
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)
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