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Document type:
Journal Article; Article
Author(s):
Gilles, S; Jacoby, D; Blume, C; Mueller, MJ; Jakob, T; Behrendt, H; Schaekel, K; Traidl-Hoffmann, C
Title:
Pollen-derived low-molecular weight factors inhibit 6-sulfo LacNAc+ dendritic cells' capacity to induce T-helper type 1 responses.
Abstract:
Evidence is accumulating that the pollen exsudate contains an array of non-allergenic, pro-inflammatory and immunomodulatory substances acting on the innate and adaptive immune system. In this context, pollen-associated E(1)-phytoprostanes (PPE(1)) were shown to licence human monocyte-derived dendritic cells for T-helper type 2 (Th2) polarization of naïve T cells.This study aims at analysing the impact of pollen-associated lipid mediators on cytokine secretion and maturation of 6-sulfo LacNAc(+)...     »
Journal title abbreviation:
Clin Exp Allergy
Year:
2010
Journal volume:
40
Journal issue:
2
Pages contribution:
269-78
Language:
eng
Fulltext / DOI:
doi:10.1111/j.1365-2222.2009.03369.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20210806
Print-ISSN:
0954-7894
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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