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Title:

Environmental polycyclic aromatic hydrocarbons (PAHs) enhance allergic inflammation by acting on human basophils.

Document type:
Comparative Study; Journal Article; Article
Author(s):
Schober, W; Lubitz, S; Belloni, B; Gebauer, G; Lintelmann, J; Matuschek, G; Weichenmeier, I; Eberlein-König, B; Buters, J; Behrendt, H
Abstract:
Diesel exhaust particles (DEPs) have been implicated in the worldwide increased incidence of allergic airway diseases over the past century. There is growing evidence that DEP-associated polycyclic aromatic hydrocarbons (PAHs) participate in the development and maintenance of immunoglobulin (Ig) E-mediated allergic diseases. To address this issue we investigated the impact of U.S. Environmental Protection Agency (EPA) priority PAHs as well as of PAH-containing airborne extracts on antigen-induce...     »
Journal title abbreviation:
Inhal Toxicol
Year:
2007
Journal volume:
19 Suppl 1
Pages contribution:
151-6
Language:
eng
Fulltext / DOI:
doi:10.1080/08958370701496046
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17886062
Print-ISSN:
0895-8378
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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