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Titel:

Matrix metalloproteinase-12 expression correlates with local recurrence and metastatic disease in non-small cell lung cancer patients.

Dokumenttyp:
Journal Article; Article
Autor(en):
Hofmann, HS; Hansen, G; Richter, G; Taege, C; Simm, A; Silber, RE; Burdach, S
Abstract:
PURPOSE: Non-small cell lung cancer (NSCLC) is a very common and aggressive malignancy. Survival after resection of tumor is especially determined by the occurrence of distant metastasis. Matrix metalloproteinases (MMP) support this metastatic process by degradation of the extracellular matrix. EXPERIMENTAL DESIGN: We used DNA microarray technology to examine the expression of 22 MMPs in 89 surgically treated NSCLC patients. Validation of microarray results was done using reverse transcription-P...     »
Zeitschriftentitel:
Clin Cancer Res
Jahr:
2005
Band / Volume:
11
Heft / Issue:
3
Seitenangaben Beitrag:
1086-92
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15709175
Print-ISSN:
1078-0432
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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