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Titel:

CCR10 is expressed in cutaneous T-cell lymphoma.

Dokumenttyp:
Journal Article; Article
Autor(en):
Notohamiprodjo, M; Segerer, S; Huss, R; Hildebrandt, B; Soler, D; Djafarzadeh, R; Buck, W; Nelson, PJ; von Luettichau, I
Abstract:
Cutaneous T-cell lymphoma (CTCL) is characterized by recruitment of malignant T-cell clones into the skin. The mechanisms involved in tumor homing are still not fully elucidated, though chemokines and chemokine receptors have been suggested to play a role in the pathogenesis. Here, we demonstrate extensive expression of CCR10 in skin biopsies of patients with Sezary syndrome (SS, n = 3), mycosis fungoides (MF, n = 2) and unspecified CTCL (n = 3). In addition, we expand prior findings of CXCR3 ex...     »
Zeitschriftentitel:
Int J Cancer
Jahr:
2005
Band / Volume:
115
Heft / Issue:
4
Seitenangaben Beitrag:
641-7
Sprache:
eng
Volltext / DOI:
doi:10.1002/ijc.20922
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15700309
Print-ISSN:
0020-7136
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie; Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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