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Title:

PET-based human dosimetry of 18F-galacto-RGD, a new radiotracer for imaging alpha v beta3 expression.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Beer, AJ; Haubner, R; Wolf, I; Goebel, M; Luderschmidt, S; Niemeyer, M; Grosu, AL; Martinez, MJ; Wester, HJ; Weber, WA; Schwaiger, M
Abstract:
(18)F-Galacto-RGD is a new tracer for PET imaging of alpha v beta3, a receptor involved in a variety of pathologic processes including angiogenesis and metastasis. Our aim was to study the dosimetry of (18)F-galacto-RGD in humans. METHODS: Eighteen patients with various tumors (musculoskeletal tumors [n = 10], melanoma [n = 5], breast cancer [n = 2], or head and neck cancer [n = 1]) were examined. After injection of 133-200 MBq of (18)F-galacto-RGD, 3 consecutive emission scans from the thorax t...     »
Journal title abbreviation:
J Nucl Med
Year:
2006
Journal volume:
47
Journal issue:
5
Pages contribution:
763-9
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16644745
Print-ISSN:
0161-5505
TUM Institution:
Frauenklinik und Poliklinik; Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für Orthopädie und Sportorthopädie; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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