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Titel:

Complexes of syndapin II with dynamin II promote vesicle formation at the trans-Golgi network.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Kessels, MM; Dong, J; Leibig, W; Westermann, P; Qualmann, B
Abstract:
The role of dynamin and so-called accessory proteins in endocytosis is well established. However, molecular details of the function(s) of dynamin II at the Golgi are largely unclear. We demonstrate that the ubiquitously expressed syndapin II isoform interacts with the proline-rich domain (PRD) of dynamin II through its Src-homology 3 (SH3) domain. Co-immunoprecipitation of endogenous syndapin II and dynamin II, and successful reconstitutions of such complexes at membranes in COS-7 cells, show th...     »
Zeitschriftentitel:
J Cell Sci
Jahr:
2006
Band / Volume:
119
Heft / Issue:
Pt 8
Seitenangaben Beitrag:
1504-16
Sprache:
eng
Volltext / DOI:
doi:10.1242/jcs.02877
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16551695
Print-ISSN:
0021-9533
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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